HAMILTON, ON, Dec. 7, 2021 — Researchers have developed a test to reveal bacterial contamination in dairy products well before they have a chance to reach anyone’s lips.
Researchers at McMaster University, with support provided by Toyota Tsusho Canada, Inc., have proven a method that will allow producers, packagers and retailers to detect bacterial contamination in milk products simply by reading a signal from a test printed inside every container.
The technology can be adapted to detect the most common food pathogens and is also expected to be effective for use with other foods and beverages.
Once it becomes widely available, the McMaster and Toyota Tsusho hope it will make the food supply safer and significantly reduce food waste.
The research has been published today in the nanotechnology journal ACS Nano.
The test in its current form works by isolating even trace amounts of infectious bacteria in milk products – a technical challenge that until now has been difficult to manage.
“Milk is a very rich environment whose complex biology can mask the presence of pathogens, making it hard to find them,” explains Tohid Didar, a Canada Research Chair in the McMaster School of Biomedical Engineering and an author on the paper. “In terms of the technical challenge, it’s similar to blood.”
The test works by printing the inner surface of a container with a tasteless, food-safe patch that repels everything but the target organisms, using a biosensor that triggers a change in the patch when such organisms are detected.
The researchers are working with Toyota Tsusho Canada, Inc., an indirect subsidiary of Toyota Tsusho Corporation in Japan, to develop and market a working prototype.
“We chose milk as a demonstration of the technology because it is so challenging. Knowing the technology works in such a complex solution means it can work with other forms of packaged food products, such as canned soup or tuna,” says co-author Carlos Filipe, McMaster’s Chair of Chemical Engineering.
Reducing illness and food waste aligns well with Toyota Tsusho Canada’s values, explained Toyota Tsusho Canada Inc. Vice President Grant Town.
“Whenever we work to generate new business, it must provide a benefit to society,” Town said. “Reducing food waste will benefit everyone, and Toyota Tsusho Canada sees this as a great opportunity.”
The research is part of an ongoing, broader effort to establish McMaster as a centre for the development of real-time sensors, pathogen-repellent materials and other products that improve food safety.
The authors of the new research seeded whole milk with E. coli to prove the technology can detect even trace amounts of the bacterium.
Having been proven effective, the researchers say, the detection technology can readily be applied to other food-borne pathogens, such as listeria and clostridium. Yingfu Li, a professor of Biochemistry and Biomedical Sciences and a co-author of the paper, had previously identified various biosensors that can detect specific pathogens.
A test patch covering multiple pathogens could be printed on or otherwise incorporated into many forms of packages, including cartons, plastic tubs, milk bags and bottles so that it can be read, either visually or with a scanner, without opening the package.
The near-term goal is to make the technology available to manufacturers, distributors and retailers, but if it is widely adopted, consumers could one day use handheld scanners to check foods immediately before consumption.
MCMASTER UNIVERSITY is a research-intensive public university in Hamilton, Ontario, dedicated to advancing human and societal health and well-being. Founded in 1887, McMaster is ranked in the world's Top 100 by the Times Higher Education World University Rankings. With a total student population of more than 33,000, McMaster welcomes students from 120 countries as well as Canada.
TOYOTA TSUSHO CANADA, INC. is a multi-market, multi-business enterprise, and is part of the Toyota Tsusho group of companies, which has been operating in North America for approximately 60 years. The Toyota Tsusho group of companies engage in various business enterprises in more than 120 countries and employ approximately 58,000 members worldwide, all striving to contribute to the creation of a prosperous society.
Method of Research
Subject of Research
LISzyme Biosensors: DNAzymes Embedded in an Anti-Biofouling Platform for Hands-Free Real-Time Detection of Bacterial Contamination in Milk
Article Publication Date