Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This book series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field.
Volume 11 of this series brings together reviews covering immunotherapy of sepsis, new antimalarials, and the medicinal use of onions for respiratory diseases, among other topics.
Topics included in this volume are:
- Heme-oxygenase and autophagy connected as a cytoprotective mechanism: potential therapeutic target
- Development of recombinant therapeutic proteins in animal cells: Challenges and solutions
- Artemisinin Analogues as a Novel Class of Antimalarial Agents: Recent Developments, Current Scenario and Future Perspectives
- The effects of Allium cepa and their derivatives on respiratory diseases and the possible mechanisms of these effects
- Immunotherapy of Sepsis
About the Author:
Atta-ur-Rahman,FRS, Ph.D. in Organic Chemistry from Cambridge University (1968) has 1,232 international publications (45 international patents and 341 books). He received the following awards: Fellow Royal Society (FRS) London (2006), UNESCO Science Prize (1999), Honorary Life Fellow Kings College, Cambridge University (2007), Academician (Foreign Member) Chinese Academy of Sciences (2015), Highest Civil Award for Foreigners of China (Friendship Award, 2014), High Civil Award Austria ("Grosse Goldene Ehrenzeischen am Bande") (2007), Foreign Fellow Chinese Chemical Society (2013), Sc.D. Cambridge University (UK) (1987), TWAS (Italy) Prize (2009). He was the President of Network of Academies of Sciences of Islamic Countries (NASIC), Vice President TWAS (Italy), Foreign Fellow Korean Academy of Science & Technology, President Pakistan Academy of Sciences (2003-2006) and (2011 — 2014). He was the Federal Minister for Science and Technology of Pakistan (2000 2002), Federal Minister of Education (2002) and Chairman Higher Education Commission/Federal Minister (2002-2008), Coordinator General of COMSTECH (01C Ministerial Committee) (1996-2012), and the Editor-in-Chief of Current Medicinal Chemistry.
Keywords:
Heme-oxygenase and autophagy, recombinant therapeutic proteins, Artemisinin Analogues ,Medical use of onion, Reactive oxygen species, Immunogenicity, Neutralizing Antibodies, Multi-drug Resistance, Thiosulphinates Septic shock.
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