News Release

Children with higher exposure to air pollution and lower exposure to green space have 62% increased risk of ADHD

Peer-Reviewed Publication

Barcelona Institute for Global Health (ISGlobal)

Children living in areas with higher air pollution due to PM2.5 particles and very low levels of green space might have up to 62% increased risk of developing ADHD. On the contrary, children living in greener and less polluted areas have a 50% lower risk of developing the disorder. These are the conclusions of a paper published in Environment International with data from 37,000 children from Vancouver (Canada). The study was led by Matilda van den Bosch, researcher at the Barcelona Institute for Global Health (ISGlobal), a centre supported by the ”la Caixa” Foundation.

The aim of this scientific work was to investigate the possible associations between exposure to greenness, air pollution and noise in early life with later incidence of ADHD, one of the most prevalent neurodevelopmental disorders, which affects up to approximately 5-10% children and adolescents. One of the goals of the study was to evaluate possible joints effects of these exposures in relation to ADHD.

The study used administrative data of births in Metro Vancouver from 2000 to 2001 and retrieved data on ADHD cases from hospital records, physician visits and prescriptions. The percentage of green space in the participants’ neighbourhood was estimated with a novel and precise satellite metric, while the residential levels of two air pollutants —NO2 and PM2.5— as well as noise levels were estimated using available exposure models. Finally, the possible associations between the three environmental exposures and ADHD were assessed using a statistical model that allowed to determine hazard ratios.

The researchers were able to identify 1,217 cases of ADHD, equivalent to a 4.2% of the total study population. The green space analysis revealed that participants living in areas with a greater percentage of vegetation had a lower risk of ADHD. More specifically, the results show that a 12% increase in vegetation percentage was associated with a 10% reduction in the risk of ADHD.

Regarding air pollution, the opposite association was observed with PM2.5: participants with a higher exposure to fine particles had higher risk of ADHD (every 2.1 µg increase in the levels of PM2.5 translated into an 11% increase in the risk of ADHD).

No associations were found for the rest of environmental exposures assessed: NO2 and noise.

Joint effects of PM2.5 and vegetation

The results are consistent with previous studies, which found associations between green space and air pollution, respectively, with ADHD. However, most of the research conducted until now focused on the evaluation of single exposures and rarely evaluated joint effects of multiple environmental exposures.

“We observed that children living in greener neighbourhoods with low air pollution had a substantially decreased risk of ADHD. This is an environmental inequality where, in turn, those children living in areas with higher pollution and less greenness face a disproportionally greater risk”, explains lead author Matilda van den Bosch. “These associations are particularly relevant because exposures take place in early life, a crucial period for brain development where children are especially vulnerable. Importantly, these exposures are modifiable, meaning that the findings should be taken into account for healthier urban planning”, she adds.

“Our findings also show that the associations between PM2.5 and ADHD were attenuated by residential green space and vice versa, as if the beneficial effects of vegetation and the harmful effects of PM2.5 neutralized each other”, says Weiran Yuchi, researcher at the University of British Columbia (Canada) and first author of the study.


Yuchi W, Brauer M, Czekajlo A, Davies HW, Davis Z, Guhn M, Jarvis I, Jerrett M, Nesbitt L, Oberlander TF, Sbihi H, Su J, van den Bosch M. Neighborhood environmental exposures and incidence of attention deficit/hyperactivity disorder: A population-based cohort study. Environ Int. 2022 Feb 7;161:107120. doi: 10.1016/j.envint.2022.107120. Epub ahead of print. PMID: 35144157.

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