Surface enhanced Raman spectroscopy (SERS) is a technique applied in multidisciplinary research. Its use has tremendously grown in the last 40 years owing to improved nanofabrication, biomolecules extraction and sensitive signal acquisition techniques.
This book focuses on the underlying principles of SERS by emphasizing on basic concepts and background information about the subject. Chapters explain the physics of Raman spectroscopy while also indicating its relevance to designing protocols and methodologies for biosensing and imaging. The book gives updated and recent details on colloids and nanostructures, their fabrication, surface engineering and immobilization methods, all in context to SERS based biosensing.
Key Features:
- Covers basic knowledge and new research about surface enhanced Raman spectroscopy (SERS)
- Provides a complete framework on SERS based biosensing with concise chapters
- Focuses on different active molecules critical to SERS and associated developed nanoassemblies
- Presents information about ongoing research on SERS imaging applications
- Highlights bottlenecks of SERS technique in biosensing
- Includes references for further reading
This book serves as a reference book for researchers and academicians and will also provide a reasonable understanding on the topic of SERS to newcomers irrespective of their background in a simple manner. The book is of interest to all readers within the scientific community involved with Raman spectroscopy, including chemists, physicists, biologists, material scientists as well as biomedical engineers.
About the Editor/ Author:
Dr. Swati Jain has more than 9 years of research and teaching experience, having worked as assistant professor at Amity Institute of Nanotechnology, Amity University, Uttar Pradesh, India. She is the recipient of a doctoral degree from the eminent Indian Institute of Technology, Delhi, in the field of Biomedical Engineering. Her research interests are focused on the multidisciplinary field of biological chemistry as a tool to answer questions on biomedical disciplines of sensor analytics. Dr. Jain had received the prestigious Best Project award of IIT D during her Ph.D. She has extensive works in immunodiagnostics for detecting food and waterborne bacteria, toxoids and also worked towards developing size-controlled functionalized nanomaterials, rendering them amenable for biosensing applications. In addition, she has fabricated 'intelligent/smart' polymers and dendrimers for industrial usages such as oil-water splitting. Her publication repertoire includes 23 papers in peer-reviewed international journals of high repute, 4 book chapters, and several consultancy reports on materials and sensors. She is a reviewer of several international journals and is a member of the Asian Polymer Association (APA), presenting her work in international forums. As a faculty, she has also created specialised course content on biomedical applications of nanomaterials for graduate and post-graduate students. Currently, she is employed as a Scientist in the Department of Science and Technology, India.
Dr. Sruti Chattopadhyay is working as a Women Scientist at the Center for Biomedical Engineering (CBME), Indian Institute of Technology Delhi. She has more than 22 years of research experience in India and abroad (USA) and has enriched her knowledge of the interdisciplinary field of polymers, biomaterials, nanotechnology, immunodiagnostics, and antimicrobials. She had received her doctorate degree from National Chemical Laboratory (NCL), Pune, India, and did her post-doctoral research work at various prestigious universities in the USA, such as Yale School of Medicine, the University of Texas at Austin, and the University of Connecticut at Storrs. She has intensively worked on the synthesis of architecturally different macromolecules such as dendrimers, star-shaped hyper-branched and ionic polymers for various industrial applications. She has over 26 publications in highly reputed international journals and has 4 book chapters to her credit. Dr. Chattopadhyay is a reviewer of many international journals and has presented her research works on innumerable international platforms. Dr. Chattopadhyay has been the principal investigator of 4 projects sponsored by the Department of Biotechnology and Department of Health Research, Government of India. Her current research focus is consecrated on biosensor design for detecting pathogenic bacteria through fluorescence and Surface-Enhanced Raman spectroscopy. She supervises as well as offers courses for B. Tech, M. Tech and Ph.D. students at CBME, IIT Delhi.
Keywords:
Biosensor, Pathogen detection, Raman scattering, Point-of-care diagnostics, Resonance, Enhancement Factors, Amyloid, Continuous glucose monitoring, Stokes and Anti-stokes, Nanofabrication, Neurotransmitters, Single molecule detection, Biosynthesis, Vibrational spectroscopy.
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