News Release

Can a blood test help diagnose skin cancer?

Peer-Reviewed Publication

Wiley

New research in Advanced NanoBiomed Research indicates that testing an individual’s blood can reveal the presence of circulating melanoma cells. Such tests may allow patients to forego invasive skin biopsies to determine whether they have skin cancer.

The test uses what’s called the Melanoma-specific OncoBean platform conjugated with melanoma-specific antibodies. Investigators at the University of Michigan showed that the test can be used not only to diagnose melanoma but also to evaluate whether all cancer cells have been successfully removed after skin cancer surgery.

"This is the first comprehensive study of circulating tumor cells—or CTCs—to evaluate the efficacy of surgery using microfluidic systems in melanoma, including changes in the number of CTCs, CTC cluster configuration, and gene expression profiling,” said first author, Yoon-Tae Kang, PhD. “CTCs have the potential to pinpoint treatment resistance and recurrence, and can be a valuable biomarker to non-invasively monitor for disease progression,” added corresponding author Sunitha Nagrath, PhD. 

URL Upon Publication: https://onlinelibrary.wiley.com/doi/10.1002/anbr.202100083

Additional Information

NOTE: The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact:

Dawn Peters +1 781-388-8408 (US)
newsroom@wiley.com
Follow us on Twitter @WileyNews

About the Journal

Advanced NanoBiomed Research provides an Open Access home for cutting-edge nanomedicine, bioengineering and biomaterials research aimed at improving human health. The journal captures a broad spectrum of research from increasingly multi- and interdisciplinary fields of the traditional areas of biomedicine, bioengineering and health-related materials science as well as precision and personalized medicine, drug delivery, and artificial intelligence-driven health science. 

About Wiley

Wiley is a global leader in research and education, unlocking human potential by enabling discovery, powering education, and shaping workforces. For over 200 years, Wiley has fueled the world’s knowledge ecosystem. Today, our high-impact content, platforms, and services help researchers, learners, institutions, and corporations achieve their goals in an ever-changing world. Visit us at  Wiley.com, like us on Facebook and follow us on Twitter and LinkedIn.


Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.