CRC is a complex disease caused by the interaction of hereditary and environmental factors, which can be classified based on the importance of each of these factors. CRCs are most commonly seasonal (70-80%), with age being the most important risk factor; hereditary variants account for only a small percentage of cases. The accumulation of hereditary and epigenetic modifications leads to colorectal cancer. Adenomas are the source of the most advanced CRCs (adenoma-carcinoma sequence). The neoplastic transfer cycle, which refers to the time it takes to detect and remove these adenomas before they progress to invasive carcinoma, is estimated to last about 10-15 years. Colorectal cancer (CRC) has three main carcinogenesis pathways that are currently being debated. This book examines the most fundamental clinical and medical methods for the treatment of colorectal cancer. In addition, we focus on recent advances in colorectal cancer science as well as key mechanisms involved in colorectal cancer treatment. The chapters in this book Cancer Diagnosis and Therapeutic are organized in such a way that even readers who have no prior knowledge of the subject will learn about it. As a result, the contents of the book are divided into eleven chapters.
About the Editors
Dr. Sankha Bhattacharya did his Post Doctorate from the Indian Institute of Technology (BHU),India in cancer nanomedicine and molecular pharmacology. He did his Ph.D. from the School of Pharmacy, RK University, India. He is currently serving as an Associate Professor in the Department of Pharmaceutics, School of Pharmacy & Technology Management. He has published more than 25 national and 41 international papers in high-impact factor and peer-reviewed journals. In 2016, he was awarded Minor Research Fellow (MRF) from Gujarat Council on Science and Technology (GUJCOST /MRP/2015-16/2677) for his contribution to cancer research.
Dr. Amit Page did Ph. D (2015) from SVKM's NMIMS, on the topic Angiogenesis and its Modification in Developing Therapeutic Agents. He pursued his graduation in Pharmacy (1 998) and Post-Graduation (2002) in Biopharmaceutics from Shivaji University, Kolhapur, India. He is currently serving as an Assistant Professor in the Department of Pharmaceutics, School of Pharmacy & Technology Management with about 19 years of Teaching and Research experience. He has six publications to his credit, along with one book on Biopharmaceutics and three book chapters on the global platform. He has been a resource person for community Pharmacists on behalf of pharmacy Council of India, Maharashtra State.
Saurabh Maru is a Researcher and Academician, working as Assistant Professor at SPTM, NMIMS, Maharashtra, with 16.5 years of research and teaching experience. He is serving as Associate Faculty of IITB. He received awards from organizations like IUPHAR, USA & IPS, NITIE (UN & Gol), DAE-BRNS, IITB, SAS Pvt. Ltd., IACR, IPA, IPC, APTI. He has MoUs as PI and three industry and one internationally funded project. He has 13 publications, 2 international patents, 5 Indian patent applications, 2 book chapters. He is Founder of a socio-scientific initiative NIROG Facilitator Network working for remotely residing tribal people, facilitated more than 4 lakh patients at government hospitals and for government policies.
Dr. Shilpa Dawre did her Ph.D (Tech) and M.Pharm from Institute of Chemical Technology, Mumbai (India) in Pharmaceutics. She is currently working as an Assistant Professor in the Department of Pharmaceutics, School of Pharmacy & Technology Management, Maharashtra, India, with 11 years of Research and Industrial experience. She is an author of many national/ international papers and two book chapters on the global platform. She had published two patents (01 international and 01 national). She is award winner of Biotechnology Entrepreneurship Student Team- Association of Biotechnology Led Enterprises 2017, organized by the Department of Biotechnology (DBT), India. She is the receipt of fellowships and fundings from government bodies like the UGC-SAP, DBT, and Indian ICMR, GOI.
Keywords:
Colorectal Cancer, Sigmoidoscopy, Histopathology, Nanoparticles, Chemotherapy, Prodrugs, Stages of cancer, Theranostics, Targeted therapies, Electrocoagulation, Signaling pathway, Endoscopic treatment, Apoptosis, Microsatellite instability, Chromosomal instability, Colonoscopy, Radiotherapy, Super magnetic iron-oxide nanoparticles, Colonoscopy, Electrocoagulation.
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