News Release

Effectiveness associated with Pfizer/BioNTech vaccine against emergency department, urgent care encounters for SARS-CoV-2 infection among adolescents

JAMA Network Open

Peer-Reviewed Publication

JAMA Network

About The Study: The findings of this study including 3,168 adolescents suggest that two doses of the Pfizer/BioNTech COVID-19 vaccine were associated with high levels of protection against emergency department and urgent care encounters related to the Delta and Omicron variants of SARS-CoV-2 in the first few months after vaccination. However, effectiveness waned over time, especially against Omicron. A third dose of the Pfizer/BioNTech vaccine was associated with improved protection against Omicron beyond that seen initially after two doses, underscoring the importance of boosters for adolescents ages 12 to 17.

Authors: Sara Y. Tartof, Ph.D., M.P.H., of Kaiser Permanente Southern California in Pasadena, is the corresponding author.

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Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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