These risk factors included male sex, older age, smoking, alcohol consumption, atrial fibrillation, use of anti-hypertensive medications, prior heart attack or stroke, established cardiovascular disease, low kidney function, high systolic blood pressure, elevated cholesterol level, and use of multiple concomitant medicines.
“Although there are some calculators to produce risk estimates of cardiovascular disease, these are not targeted at those at high risk of fracture,” said corresponding author Daniel Prieto-Alhambra, MD, PhD, of the University of Oxford, in the UK. “To our knowledge, this is the first study to identify cardiovascular disease risk factors for osteoporotic individuals using data that is routinely collected and readily available.”
URL Upon Publication: https://onlinelibrary.wiley.com/doi/10.1002/jbmr.4648
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Journal of Bone and Mineral Research
Estimating the incidence and key risk factors of cardiovascular disease in 2 patients at high risk of imminent fracture using routinely collected real-world 3 data from the UK
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