About The Study: The findings of this study of women in Denmark followed up from age 45 suggest that systemically administered (oral or transdermal) hormonal therapy before and during menopause is associated with higher risk of depression, especially in the years immediately after initiation, whereas locally administered (intravaginal or intrauterine) hormonal therapy is associated with lower risk of depression for women 54 years or older.
Authors: Merete Osler, M.D., Ph.D., D.M.Sc., of the Bispebjerg and Frederiksberg Hospitals in Frederiksberg, Denmark, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.39491?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110122
JAMA Network Open