News Release

Medicinal Chemistry Lessons From Nature (Part 1)

Book Announcement

Bentham Science Publishers

The book “Medicinal Chemistry Lessons From Nature (Part 1)“ will propose the latest discoveries in the field of compounds inspired by Nature and obtained by chemical/enzymatic modification of a natural compound in the search of biologically active molecules for the treatment of human/animal ailments and will permit the disposal of a wider arsenal for the clinicians.

The chapters will be built with the following format:

• General background on the (phyto) chemistry of the scaffold;

• General background on the pharmacological profile of the scaffold;

• Description of the proposed derivatives and their potentialities with respect to the parent compounds (with particular emphasis on the synthetic approaches and structure-activity relationships);

• In silico analysis of the crucial interactions with the biological target;

• Clinical studies and patent survey (if available) on the new and proposed structures.

All the aspects relevant for Medicinal Chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modelling studies) will be analyzed. It will guide researchers to always more concrete applications in the natural product field.

Each chapter will review on agents with common chemical features. They will be non-overlapping and focused on experimental results which can be translated into clinical ones.

The intention of this planned book series “Medicinal Chemistry Lessons From Nature (Part 1)“ is to give an overview from the latest discoveries in the pharmacological and chemical research on natural products-derived compounds spanning from the synthesis to a systematic approach of the most exciting pharmacokinetic and pharmacodynamic topics. It will be structured with innovative book setting outlines and a clear distinction between experimental and clinical results, in order to aid the reader to know at which step of the pipeline each compound is. Due to the scarcity of information of the other competing books, the Editor wants to fulfil the gap of the acquired knowledge in the last few years with the aim to provide a guide for academic and professional researchers and clinicians.


About the editor:

Prof. Simone Carradori has carried out his scientific work in Medicinal Chemistry collaborating with several foreign departments. Currently, he is an associate professor at the Department of Pharmacy of “G. d’Annunzio” University of Chieti-Pescara (Italy). The scientific activity is mainly focused on the characterization and synthesis of natural/synthetic derivatives with potential biological activity and is documented from over 225 papers in international peer-reviewed journals, 6 book chapters, 1 European patent and participations in numerous conferences as invited lecturer. Furthermore, he is “Visiting Professor” at “Faculty of Pharmacy of Bezmialem Vakif University” (Istanbul, Turkey) and member of the PhD committee at “G. d’Annunzio” University of Chieti-Pescara.

He is Editor-in-chief of “Anti-Cancer Agents in Medicinal Chemistry” (Bentham Science Publishers), co-editor of “Current Medicinal Chemistry” (Bentham Science Publisher) and “Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry” (Bentham Science Publishers).



Natural compounds, Carbonic anhydrase, hybrids, Monoamine oxidase, xanthones, Semi-synthesis, resveratrol, sesquiterpenes, combretastatin, cannabinoids, chalcones, Essential oil encapsulation, flavonoids, antimalaria, aurones, alkaloids, lignins, epigenetics, coumarins, morphinans, caffeine, noscapinoids, Biogenic amines, piperine, Quinoline derivatives, Medicinal chemistry.


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