News Release

Infant pertussis incidence trends before, after implementation of maternal Tdap vaccine

JAMA Pediatrics

Peer-Reviewed Publication

JAMA Network

About The Study: In this study of 57,460 pertussis (also known as whooping cough) cases in the United States, following maternal tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine introduction, a sustained decrease in pertussis incidence was observed among infants younger than 2 months, narrowing the incidence gap with infants ages 6 months to less than 12 months. These findings suggest that maternal Tdap vaccination is associated with a reduction in pertussis burden in the target age group (younger than 2 months) and that further increases in coverage may be associated with additional reductions in infant disease. 

Authors: Tami H. Skoff, M.S., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.

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