Characterization and determinant factors of critical illness and in-hospital mortality of COVID-19 patients: A retrospective cohort of 1,792 patients in Kenya
Globally, there is an anticipated epidemiological heterogeneity of COVID-19 patients. No epidemiological studies validated the epidemiological characterization of COVID-19 patients in African settings. Previous studies identified some risk factors for severe COVID-19 and mortality in developed countries. Previous epidemiological studies have also reported that hospitalized COVID-19 patients are linked with advanced age and underlying medical conditions.
The study finds that COVID-19 individuals with comorbidities (such as CVDs, chronic lung disease, cancer, and diabetes) are at a higher risk of severe disease progression. Additionally, oxygen saturation levels, advanced age, and gender predict ICU admission and mortality among COVID-19 patients. This study informs on predictors of ICU admission and hospital mortality and the survival rate of COVID-19 in the African settings, where the triple disease burden from emerging diseases, endemics, and non-communicable diseases is a challenge.
Keywords: Comorbidities, Critical illness, ICU, COVID-19, SARS-CoV-2
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Article reference: Isinta M Elijah, Endawoke Amsalu, Xuening Jian, Mingyang Cao, Eric K Mibei, Danvas O Kerosi, Francis G Mwatsahu, Wei Wang, Faith Onyangore, Youxin Wang, Characterization and determinant factors of critical illness and in-hospital mortality of COVID-19 patients: A retrospective cohort of 1,792 patients in Kenya, Biosafety and Health, Volume 4, Issue 5, 2022, Pages 330-338, ISSN 2590-0536, https://doi.org/10.1016/j.bsheal.2022.06.002
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