News Release

'Other' race/ethnicity linked to higher suicide and overdose risk in military members with mild TBI

Researchers cite 'perfect storm' of brain injury, opioids, and related risk factors

Peer-Reviewed Publication

Wolters Kluwer Health

March 8, 2023 – Previous studies have reported high rates of death by suicide and drug overdose – including opioid overdose – in military service members with a history of mild traumatic brain injury (mTBI). A new study finds that those risks are highest among military members with mTBI who identify their racial/ethnic status as "Other," as opposed to standard racial/ethnic categories, reports the March/April issue of the Journal of Head Trauma Rehabilitation (JHTR). The official journal of the Brain Injury Association of AmericaJHTR is published in the Lippincott portfolio by Wolters Kluwer.

"In our study of military members with mTBI, mortality rates for suicide and drug and opioid overdose were consistently higher among those who self-identified as 'Other' – a category often selected by multiracial or other individuals who do not see themselves as fitting into White, Black, Hispanic, or other standard racial/ethnic categories," comments lead author Nazanin Bahraini, PhD, of VA Rocky Mountain Mental Illness Research Education and Clinical Center for Suicide Prevention and University of Colorado Anschutz Medical Campus, Aurora.

Racial/ethnic disparities in suicide and overdose deaths among military members with mTBI

In military as well as civilian populations, mTBI is a documented risk factor for suicide and death from drug overdose. "Among military service members, disparities in external causes of death, such as suicide and drug overdose associated with TBI, may be further compounded for members of minoritized groups," Dr. Bahraini and coauthors write.

Using Department of Defense databases, the researchers identified 356,514 service members diagnosed with mTBI during military service between 1999 and 2019. Most served during the conflicts in Iraq and Afghanistan.

Based on data from the National Death Index, 1,105 of the military members with mTBI died of suicide (0.31% of the study population) and 886 died from drug overdose (0.25%), of which 595 were from opioid overdose (0.17%). More than half of deaths from these three causes occurred in members who were between 18 to 24 years old at the time of their mTBI.

Rates of all three causes of death were highest in the "Other" racial/ethnic category. Although military members in the "Other" group made up only 7.38% of the study sample, they accounted for 17.83% of suicides, 21.44% of drug overdose deaths, and 21.01% of opioid overdose deaths.

After accounting for the effect of age, rates of all three outcomes remained higher among service members who identified their race/ethnicity as "Other," compared to individuals who identified with the five more traditionally categorized racial/ethnic groups, with the exception of service members in the American Indian/Alaska Native category, who comprised 1.48% of the study sample. Relative risk of suicide in the "Other" group was about twice as high as in White/non-Hispanic military members and five times higher than in Black/non-Hispanic members.

'Perfect storm' of TBI, opioids, and other risk factors for overdose and suicide

Military service members in the "Other" category also had a higher relative risk of death from drug overdose. Age-adjusted risk of drug overdose death was more than three  times higher than for White/non-Hispanic military members, five times higher than for Hispanic or Asian American/Pacific Islander members, and 11 times higher than for Black/non-Hispanic members. Opioid overdose deaths were up to 3.5 times more common than for members of the five traditional racial/ethnic categories.

These findings add to previous evidence that people with TBI are more likely to receive prescription opioids and to have other risk factors – creating a "perfect storm" of risk factors for opioid misuse and related consequences. "[A]mong military members with mTBI, over two-thirds of drug-overdose deaths involved an opioid," Dr. Bahraini and coauthors note.

This study highlights the importance of examining racial/ethnic disparities in suicide and drug overdose mortality rates in military members with mTBI," the researchers conclude. "[B]ecause choices for race/ethnicity were constrained to a single choice with no category options for multiple races, the racial and ethnic identities of military members in this higher-risk group remain unclear."

Dr Bahraini comments: "Race and ethnicity are social constructs that are continually evolving, yet current data collection methods do not account for the significant heterogeneity within groups. We could gain a clearer picture if we were able to examine more detailed subgroups, including those who self-identify with multiple race and ethnicity groups as well as subgroups differentiated by national origin. More importantly, we need to better understand how the different experiences of these subgroups – for example, discrimination – may contribute to health disparities."

Read [Racial and Ethnic Differences in Deaths by Suicide, Drug Overdose, and Opioid-Related Overdose in a National Sample of Military Members With Mild Traumatic Brain Injury, 1999-2019]

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About The Journal of Head Trauma Rehabilitation

The Journal of Head Trauma Rehabilitation is a leading, peer-reviewed resource that provides up-to-date information on the clinical management and rehabilitation of persons with traumatic brain injuries. Six issues each year aspire to the vision of “knowledge informing care” and include a wide range of articles, topical issues, commentaries and special features. It is the official journal of the Brain Injury Association of America.

About the Brain Injury Association of America

The Brain Injury Association of America is the country’s oldest and largest nationwide brain injury advocacy organization. Our mission is to advance awareness, research, treatment and education and to improve the quality of life for all individuals impacted by brain injury. Through advocacy, we bring help, hope and healing to millions of individuals living with brain injury, their families and the professionals who serve them. 

About Wolters Kluwer

Wolters Kluwer (WKL) is a global leader in professional information, software solutions, and services for the healthcare; tax and accounting; governance, risk and compliance; and legal and regulatory sectors. We help our customers make critical decisions every day by providing expert solutions that combine deep domain knowledge with specialized technology and services.

Wolters Kluwer reported 2021 annual revenues of €4.8 billion. The group serves customers in over 180 countries, maintains operations in over 40 countries, and employs approximately 20,000 people worldwide. The company is headquartered in Alphen aan den Rijn, the Netherlands.

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