News Release

Prompt treatment for functional neurological disorder in children is highly effective

Successful treatment programs can be established in a variety of health care settings

Peer-Reviewed Publication

Wolters Kluwer Health

March 9, 2023 – Treatment is scarce for functional neurological disorder (FND), which requires a multidisciplinary approach. A special report published in the March/April issue of Harvard Review of Psychiatry (HRP) aims to show clinicians and institutions around the world what is needed to establish effective community treatment programs for FND, as well as hospital inpatient and outpatient interventions, in their own health care settings. HRP is published in the Lippincott portfolio by Wolters Kluwer.

Functional neurological disorder, formerly called conversion disorder, involves the biological embedding of lived experience in the body and brain. This is the process whereby stress, the social environment, or early experience affects the body’s biological systems. The embedding culminates in stress-system activation or dysregulation and aberrant changes in neural network function. Patients with FND have neurologic symptoms such as limb weakness, tremors, gait difficulties, seizures, or cognitive problems that are not explained by traditional neurological disorders.

As many as a fifth of children and adolescents seen in pediatric neurology clinics are found to have FND. An estimated 63% to 95% of these patients can fully recover if they receive prompt diagnosis and proper treatment.

A treatment gap exists worldwide for pediatric patients with FND

Unfortunately, many children with FND do not receive the care they need. Kasia Kozlowska, MD, PhD, a child and adolescent psychiatrist at The Children’s Hospital at Westmead in Sydney, Australia, and colleagues explain the scarcity of treatment is global, in part "the result of long-standing stigma and ingrained belief that patients with FND do not suffer from a real ("organic") disorder and that they therefore do not require, or even deserve, treatment."

In a Perspectives article in HRP, Dr. Kozlowska and her colleagues describe the elements of a biopsychosocial mind–body program intervention they designed that has been successful for managing FND in children and adolescents.

A seven-component treatment program

Over almost 30 years, the Mind–Body Program for children with FND at The Children’s Hospital at Westmead has delivered inpatient care to hundreds of patients with FND. In collaboration with community-based clinicians, the program’s staff has also designed individualized treatment for hundreds of outpatients.

The authors say that although care is personalized, their interventions for FND always have seven elements: prompt medical/neurological assessment and diagnosis by a physician; triaging the referral for a holistic (biopsychosocial) assessment; a holistic, biopsychosocial assessment of the child and family; co-constructing a formulation with the child and family to identify factors that contribute to and maintain the child’s symptoms; assembling a personalized treatment plan; implementing the plan; and building resilience and preventing relapse. The article describes each of these elements in detail.

Most health care professionals working in pediatrics can easily add an FND-informed skill set to their current clinical practice, Dr. Kozlowska’s group notes:

  • Pediatricians and pediatric neurologists already have the skills necessary to diagnose FND: they simply need to learn to recognize the rule-in signs for FND and to practice communicating an FND diagnosis.
  • Physical therapists can shift their approach from a "musculoskeletal framework that focuses attention on the problem area" to a framework in which the patient’s attention is drawn away from the symptoms, with particular focus on building a therapeutic relationship, using play, and applying interventions in ways that address the problem indirectly.
  • Mental health clinicians already know how to conduct a biopsychosocial assessment and provide individual and family interventions; they just need to understand "the somatic narrative," the bottom-up approach to emotion regulation, and strategies for managing focus of attention.

Dr. Kozlowska and colleagues emphasize that FND is a positive diagnosis (rather than a diagnosis of exclusion) that should be made by a pediatrician, neurologist, neuropsychiatrist, family doctor, or other physician. "[C]linical interactions during the assessment process are, in themselves, a potentially valuable therapeutic intervention."

Read [Evidence-Based Mind-Body Interventions for Children and Adolescents with Functional Neurological Disorder]

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About HRP

Harvard Review of Psychiatry is the authoritative source for scholarly reviews and perspectives on a diverse range of important topics in psychiatry. Founded by the Harvard Medical School Department of Psychiatry, the journal is peer-reviewed and not industry sponsored. It is the property of President and Fellows of Harvard College and is affiliated with all of the Departments of Psychiatry at the Harvard teaching hospitals.

Articles encompass all major issues in contemporary psychiatry, including (but not limited to) neuroscience, psychopharmacology, psychotherapy, history of psychiatry, and ethics. In addition to scholarly reviews, perspectives articles, and columns, the journal includes a Clinical Challenge section that presents a case followed by discussion and debate from a panel of experts.

About Wolters Kluwer

Wolters Kluwer (WKL) is a global leader in professional information, software solutions, and services for the healthcare; tax and accounting; governance, risk and compliance; and legal and regulatory sectors. We help our customers make critical decisions every day by providing expert solutions that combine deep domain knowledge with specialized technology and services.

Wolters Kluwer reported 2021 annual revenues of €4.8 billion. The group serves customers in over 180 countries, maintains operations in over 40 countries, and employs approximately 20,000 people worldwide. The company is headquartered in Alphen aan den Rijn, the Netherlands.

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