News Release

Can low-carbohydrate or low-fat diets prolong life in middle-aged and older adults?

Peer-Reviewed Publication


Short-terms clinical trials have demonstrated the health benefits of low-carbohydrate diets (LCDs) and low-fat diets (LFDs) for weight loss and heart protection. Now a study published in the Journal of Internal Medicine looks at the effects of these diets on mortality in middle-aged and older adults.

In the study of 371,159 individuals aged 50 to 71 years, 165,698 deaths occurred over a median follow-up of 23.5 years.

A healthy LFD—characterized by low intake of saturated fat and high intakes of plant protein and high-quality carbohydrates—was related to fewer deaths from all causes, from cardiovascular diseases, and from cancers. In contrast, an overall LCD and an unhealthy LCD were associated with significantly higher total, cardiovascular, and cancer mortality rates. A healthy LCD was associated with slightly lower death rates.

“Our results support the importance of maintaining a healthy LFD with less saturated fat in preventing all-cause and cause-specific mortality among middle-aged and older people,” the authors wrote.

URL upon publication:


Additional Information
The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact: Sara Henning-Stout,

About the Journal
The Journal of Internal Medicine (JIM) is an international peer-reviewed scientific journal in continuous publication since 1863. JIM publishes original work in clinical science from bench to bedside covering a broad field of internal medicine and its subspecialties. JIM features original articles, reviews, brief reports and research letters.

About Wiley
Wiley is one of the world’s largest publishers and a global leader in scientific research and career-connected education. Founded in 1807, Wiley enables discovery, powers education, and shapes workforces. Through its industry-leading content, digital platforms, and knowledge networks, the company delivers on its timeless mission to unlock human potential. Visit us at Follow us on FacebookTwitterLinkedIn and Instagram.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.