About The Study: The findings of this systematic review and meta-analysis of secondary data from 40 studies suggest that the effectiveness of COVID-19 vaccines against laboratory-confirmed Omicron or Delta infection and symptomatic disease rapidly wanes over time after the primary vaccination cycle and booster dose. These results can inform the design of appropriate targets and timing for future vaccination programs.
Authors: Piero Poletti, Ph.D., of the Bruno Kessler Foundation in Trento, Italy, is the corresponding author.
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