News Release

Association of adverse childhood experiences with accelerated epigenetic aging in midlife

JAMA Network Open

Peer-Reviewed Publication

JAMA Network

About The Study: Adverse childhood experiences were associated with epigenetic age acceleration, a biomarker associated with various health outcomes in middle-age adults, after controlling for demographics, behavior, and socioeconomic status. These findings of the associations between early life experience and the biological aging process in midlife may contribute to health promotion in a life course perspective. 

Authors: Lifang Hou, M.D., Ph.D., and Brian Joyce, Ph.D., of the Northwestern University Feinberg School of Medicine in Chicago, are the corresponding authors. 

To access the embargoed study: Visit our For The Media website at this link 


Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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