Rising amputation rates among opioid-related hospitalizations
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Latest funded news by National Institute on Drug Abuse (NIDA)
Updates every hour. Last Updated: 20-Jun-2026 13:16 ET (20-Jun-2026 17:16 GMT/UTC)
A study examined U.S. hospitalizations from 2016–2022 to better understand how amputation rates have shifted over time and across regions.The study found that during this period, amputation rates increased among both opioid- and non-opioid-related hospitalizations, but the rise was significantly steeper among opioid-related cases—especially in the Northeast and Western United States.
New research from MUSC Hollings Cancer Center highlights a promising new approach to smoking cessation by targeting the brain’s executive control system. In a randomized clinical trial led by Hollings researcher Xingbao Li, M.D., noninvasive brain stimulation aimed at the dorsolateral prefrontal cortex helped participants reduce smoking and suppress cravings more effectively than other targeting approaches.
The findings suggest that strengthening brain regions involved in decision-making and self-control may help people to better manage the urge to smoke. The work adds to growing efforts at Hollings to expand evidence-based tobacco treatment options and better understand the brain mechanisms underlying addiction.
A 2019 vaping-related health scare reshaped how many smokers view the risks of e-cigarettes – and those perceptions still linger today. New research from MUSC Hollings Cancer Center found that smokers came to see e-cigarettes as equally or more dangerous relative to combustible cigarettes, even after the true cause of the illness was identified, which may influence decisions about quitting or switching.
“That period really changed how people think about these products,” said lead researcher Tracy Smith, Ph.D., who co-leads the Hollings Cancer Prevention and Control Program. “Even after we learned more about what caused the illness, those perceptions didn’t fully reset.”
A new paper in Nicotine and Tobacco Research finds that while research has previously found that vaping is associated with subsequently quitting smoking, that may not always be true. In fact, it appears that studies limited to people who actually want to quit smoking are less likely to find this relationship.
Most people strongly support the federal government’s reclassification of cannabis, according to a new study that used AI to analyze more than 40,000 comments in the public record.
The findings by researchers at Johns Hopkins University and the University of California San Diego, which come as the Trump administration last week reclassified state-licensed medical marijuana from a Schedule I drug to a less dangerous Schedule III, suggest the public would like to see even more reform.
The U.S. outside Puerto Rico still has a high rate of dental opioid pain medication prescription filling compared with other developed nations, despite steep drops in recent years because of guidelines spurred by the opioid crisis.