New technology that allows a University of Virginia-developed artificial pancreas system to adapt to users’ changing bodies – and lets users test changes to how the system operates – improved control of their type 1 diabetes, a study has found.

Complex illnesses are not caused by one gene but groups of genes. The number of gene combinations is too enormous to analyze comprehensively. New AI model focuses on gene expression changes to identify key genes and their collective influence on disease.

Researchers from the University of Michigan Rogel Cancer Center developed a new mouse model that shows CDK12 acts as a tumor suppressor to drive high-grade serous carcinoma arising in the mouse oviduct – the equivalent of human fallopian tube. A promising degrader targeting CDK12 and a related gene, CDK13, can destroy these tumors.