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RCas9: A programmable RNA editing tool

DOE/Lawrence Berkeley National Laboratory
Peer-Reviewed Publication

A powerful scientific tool for editing the DNA instructions in a genome can now also be applied to RNA as Berkeley Lab researchers have demonstrated a means by which the CRISPR/Cas9 protein complex can be programmed to recognize and cleave RNA at sequence-specific target sites.

Journal: Nature
Funder: Center for RNA Systems Biology, National Institutes of Health

A closer look at the perfect fluid

DOE/Lawrence Berkeley National Laboratory
Peer-Reviewed Publication

By combining data from two high-energy accelerators, nuclear scientists have refined the measurement of a remarkable property of exotic matter known as quark-gluon plasma. The findings reveal new aspects of the ultra-hot, 'perfect fluid' that give clues to the state of the young universe just microseconds after the big bang.

Journal: Physical Review C
Funder: DOE/US Department of Energy

NIH taps lab to develop sophisticated electrode array system to monitor brain act

DOE/Lawrence Livermore National Laboratory
Grant and Award Announcement

The National Institutes of Health awarded Lawrence Livermore National Laboratory a grant today to develop an electrode array system that will enable researchers to better understand how the brain works through unprecedented resolution and scale.

Funder: National Institutes of Health

Simulations reveal an unusual death for ancient stars

DOE/Lawrence Berkeley National Laboratory
Peer-Reviewed Publication

Certain primordial stars -- those 55,000 and 56,000 times the mass of our sun, or solar masses -- may have died unusually. In death, these objects -- among the universe's first generation of stars -- would have exploded as supernovae and burned completely, leaving no remnant black hole behind.

Funder: DOE/US Department of Energy

MaxBin: Automated sorting through metagenomes

DOE/Lawrence Berkeley National Laboratory
Peer-Reviewed Publication

MaxBin is an automated software program for binning the genomes of individual microbial species from metagenomic sequences developed at the Joint BioEnergy Institute.

Journal: Microbiome
Funder: US Department of Energy's Office of Science

2015 DOE JGI's science portfolio delves deeper into the Earth's data mine

DOE/Joint Genome Institute
Grant and Award Announcement

In selecting 32 new projects with samples from diverse environments for the 2015 Community Science Program (CSP), the Department of Energy Joint Genome Institute shifts 'from solving an organism's genome sequence to enabling an understanding of what this information enables organisms to do.' The total allocation of the CSP 2015 portfolio is expected to exceed 60 trillion bases -- the equivalent of 20,000 human genomes of plant, fungal and microbial genome sequences.

Funder: DOE/US Department of Energy

On the road to artificial photosynthesis

DOE/Lawrence Berkeley National Laboratory
Peer-Reviewed Publication

New experimental results from Berkeley Lab have revealed the critical influence of the electronic and geometric effects in the carbon dioxide reduction reaction.

Journal: Nature Communications

Interactive map reveals rooftop reflectance for 5 California cities

DOE/Lawrence Berkeley National Laboratory
Business Announcement

Berkeley Lab scientists use aerial imagery to create an interactive map that displays the solar reflectance (also known as albedo) of individual roofs in Bakersfield, Long Beach, Los Angeles, San Francisco, and San Jose.

Research pinpoints role of 'helper' atoms in oxygen release

DOE/SLAC National Accelerator Laboratory

Experiments at the Department of Energy's SLAC National Accelerator Laboratory solve a long-standing mystery in the role calcium atoms serve in a chemical reaction that releases oxygen into the air we breathe. The results offer new clues about atomic-scale processes that drive the life-sustaining cycle of photosynthesis and could help forge a foundation for producing cleaner energy sources by synthesizing nature's handiwork.

Decoding virus-host interactions in the oxygen-starved ocean

DOE/Joint Genome Institute
Peer-Reviewed Publication

In certain coastal areas, severe reductions in oxygen levels in the water destroy food web structure. Over the past 50 years, such oxygen minimum zones have expanded due to climate change and increased waste run-off. Reported in the journal eLife, a collaboration between researchers from the Department of Energy Joint Genome Institute, the University of British Columbia, and University of Arizona studied how viral infection influences a microbial community in one such OMZ.

Funder: US Department of Energy's Office of Science