Researchers from the U.S. Department of Energy Joint Genome Institute (DOE JGI) and collaborators at the University of Wisconsin, Madison, and the Advanced Wastewater Management Centre, University of Queensland, Australia, have published the first metagenomic study of an activated sludge wastewater treatment process. The research provides a blueprint of the genes and hence the metabolic possibilities of the wastewater environment, a view to understand how the system works and predicting and averting failures or crashes.