In the language of DNA, the common link among all living things, are lessons for interpreting the complex systems that regulate the health of planet Earth. Now, the global lesson plan includes more than 40 new genome projects, representing a cornucopia of life forms, from the important grain sorghum, to catfish, crustaceans, and a host of extreme lifestyle microbes, slated for DNA sequencing by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI).