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17-Dec-2002
BioSET licenses Brookhaven Lab's synthetic growth factor technology
DOE/Brookhaven National LaboratoryBusiness Announcement
BioSurface Engineering Technologies, Inc. (BioSET), of College Park, Maryland, has obtained an exclusive worldwide license to a novel growth factor technology developed by scientists at the U.S. Department of Energy's Brookhaven National Laboratory in collaboration with BioSET researchers. The Brookhaven-BioSET team made biologically active synthetic analogs of two growth factors, including basic fibroblast growth factor for use in wound healing and radiation protection, as well as other applications.
19-Nov-2002
Scientists reveal a new way viruses cause cells to self-destruct
DOE/Brookhaven National LaboratoryPeer-Reviewed Publication
Scientists at Brookhaven National Laboratory and their collaborators have discovered that some viruses can use the most abundant protein in the cells they are infecting to destroy the cells and allow new viruses to escape to infect others. The findings, described in the November 29, 2002, issue of the Journal of Biological Chemistry, may lead to the design of more effective antiviral remedies.
- Journal
- Journal of Biological Chemistry
- Funder
- DOE/US Department of Energy, National Institutes of Health
14-Nov-2002
Molecular film on liquid mercury reveals new properties
DOE/Brookhaven National LaboratoryPeer-Reviewed Publication
A team of scientists has grown ultrathin films made of organic molecules on the surface of liquid mercury. The results, reported in the November 15, 2002, issue of Science, reveal a series of new molecular structures that could lead to novel applications in nanotechnology.
- Journal
- Science
- Funder
- DOE/US Department of Energy, U.S.-Israel Binational Science Foundation, National Science Foundation
11-Nov-2002
Scientists identify role of important cancer protein
DOE/Brookhaven National Laboratory
Scientists from the U.S. Department of Energy's National Synchrotron Light Source located at Brookhaven National Laboratory have uncovered how a known cancer protein disrupts the normal function of human cells. This discovery, which may lead to the design of new anticancer drugs, is reported in the November 1, 2002, issue of the journal Cell.
5-Nov-2002
New tool for studying animal models of neurological and psychiatric diseases
DOE/Brookhaven National LaboratoryPeer-Reviewed Publication
Scientists at Brookhaven Lab have demonstrated that a miniature positron emission tomography (PET) scanner, known as microPET, and the chemical markers used in traditional PET scanning are sensitive enough to pick up subtle differences in neurochemistry between known genetic variants of mice. This research provides a non-invasive way to study and follow animal models for human neurological diseases, and may lead to new treatments.
- Journal
- Journal of Nuclear Medicine
- Funder
- NIH/National Institute on Alcohol Abuse and Alcoholism, DOE/US Department of Energy, National Institute on Drug Abuse
31-Oct-2002
Scientists identify role of important cancer protein
DOE/Brookhaven National LaboratoryPeer-Reviewed Publication
Scientists working at the National Synchrotron Light Source (NSLS) at the U.S. Department of Energy's (DOE's) Brookhaven National Laboratory have unveiled the details of an important cancer protein. The new results, which are reported in the November 1 issue of Cell, shed light on how this protein triggers tumor growth, and may provide ways to design new anticancer drugs.
- Journal
- Cell
- Funder
- DOE/US Department of Energy, Searle Scholar Foundation, Tobacco-Related Disease Research Program, National Institutes of Health, Rita Allen Foundation
29-Oct-2002
New technique reveals structure of thin films with high resolution
DOE/Brookhaven National LaboratoryPeer-Reviewed Publication
Scientists have developed and tested a new imaging technique that reveals the atomic structure of thin films with unprecedented resolution. For the first time, the technique has shown very precisely how the atoms of the first layers of a film rearrange under the action of the substrate on which the film is grown.
- Journal
- Nature Materials
- Funder
- DOE/US Department of Energy
12-Sep-2002
Biological serendipity: molecular details of cell membrane fusion revealed
DOE/Brookhaven National LaboratoryPeer-Reviewed Publication
For the first time, scientists have observed the molecular details of biological cells fusing together, a fleeting event never before observed at this scale. This research, which could lead to more efficient drug delivery processes and gene therapy techniques, was performed at the National Synchrotron Light Source (NSLS) at the U.S. Department of Energy's Brookhaven National Laboratory, and Rice University.
- Journal
- Science
- Funder
- DOE/US Department of Energy
26-Aug-2002
Unique structures in molybdenum blue solutions reveal possible new solute state
DOE/Brookhaven National LaboratoryPeer-Reviewed Publication
For nearly 200 years, scientists have known that the elements molybdenum and oxygen can form various large molecules, which usually impart a unique blue color to aqueous solutions. Only recently have scientists been able to isolate these molecules, but no one was able to explain their supramolecular structure in solution, until now. The unique "blackberry" structure may represent a new, stable solute state never seen before.
- Journal
- Journal of the American Chemical Society
- Funder
- DOE/US Department of Energy