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Population-specific diversity within fungi species could enable improved drug discovery

DOE/Oak Ridge National Laboratory

Scientists at Oak Ridge National Laboratory and the University of Wisconsin-Madison have discovered that genetically distinct populations within the same species of fungi can produce unique mixes of secondary metabolites, which are organic compounds with applications in medicine, industry and agriculture. The finding could open new avenues for drug discovery and provide a deeper understanding of fungal evolution.

Population-specific diversity within fungi species could enable improved drug discovery

DOE/Oak Ridge National Laboratory

Scientists at Oak Ridge National Laboratory and the University of Wisconsin-Madison have discovered that genetically distinct populations within the same species of fungi can produce unique mixes of secondary metabolites, which are organic compounds with applications in medicine, industry and agriculture. The finding could open new avenues for drug discovery and provide a deeper understanding of fungal evolution.

Tiny but mighty precipitates toughen a structural alloy

DOE/Oak Ridge National Laboratory
Peer-Reviewed Publication

Scientists at the Department of Energy's Oak Ridge National Laboratory and the University of Tennessee, Knoxville, have found a way to simultaneously increase the strength and ductility of an alloy by introducing tiny precipitates into its matrix and tuning their size and spacing. The precipitates are solids that separate from the metal mixture as the alloy cools. The results will open new avenues for advancing structural materials.

Journal: Nature
Funder: Laboratory Directed Research and Development Program of Oak Ridge National Laboratory, DOE/US Department of Energy

Story tips: Powered by nature, get on the bus, accelerating methane and more

DOE/Oak Ridge National Laboratory
Peer-Reviewed Publication

ORNL story tips: Powered by nature, get on the bus, accelerating methane, helping JET soar, charged up planning and building a better thermostat

Journal: Proceedings of the National Academy of Sciences

Biosciences chief scientist, Corporate Fellow reflects on trailblazing LGBTQIA+ presence at ORNL

DOE/Oak Ridge National Laboratory

Among Brian Davison's many accomplishments at ORNL, he's most proud of forming PRISM, a thriving employee resource group for LGBTQIA+ staff.

DOE scientists deploy creativity, speed to disrupt COVID-19

DOE/Oak Ridge National Laboratory

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques - in combination with experimental validation - to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.

ORNL names new Innovation Crossroads cohort of entrepreneurs

DOE/Oak Ridge National Laboratory
Grant and Award Announcement

Six science and technology innovators from across the United States will join the fifth cohort of Oak Ridge National Laboratory's Innovation Crossroads program in June. As the Southeast's only research and development program for entrepreneurs based at a U.S. Department of Energy national laboratory, Innovation Crossroads provides unique support to science-based startups to help advance game-changing technologies from the laboratory to the marketplace.

Single gene boosts climate resilience, yield and carbon capture in crops

DOE/Oak Ridge National Laboratory

Scientists at Oak Ridge National Laboratory have discovered a single gene that simultaneously boosts plant growth and tolerance for stresses such as drought and salt, all while tackling the root cause of climate change by enabling plants to pull more carbon dioxide from the atmosphere.

Story tips: Un-Earthly ice, buildings in the loop, batteries unbound and 3D printing for geothermal

DOE/Oak Ridge National Laboratory
Peer-Reviewed Publication

ORNL story tips: Un-Earthly ice, buildings in the loop, batteries unbound and 3D printing for geothermal.

Journal: ACS Sustainable Chemistry & Engineering
Funder: DOE/US Department of Energy, NASA

Physicists crack the code to signature superconductor kink using supercomputing

DOE/Oak Ridge National Laboratory

A team performed simulations on the Summit supercomputer at the Oak Ridge Leadership Computing Facility and found that electrons in cuprates interact with phonons much more strongly than was previously thought, leading to experimentally observed "kinks," or sudden changes, in the relationship between an electron's energy and the momentum it carries.

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