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New, detailed molecular roadmap boosts fight against endometrial cancer

DOE/Pacific Northwest National Laboratory
Peer-Reviewed Publication

Scientists have taken an unprecedented look at the proteins involved in endometrial cancer, commonly known as uterine cancer. The study offers insights about how physicians might be able to better identify which patients will need aggressive treatment and which won't, and offers clues about why a common cancer treatment is not effective with some patients.

Journal: Cell
Funder: NIH/National Cancer Institute, McNair Medical Institute and the Population Sciences Biorepository at Baylor College of Medicine, Cancer Prevention and Research Institutes of Texas (CPRIT)

Scientists learn more about the first hours of a lithium-ion battery's life

DOE/Pacific Northwest National Laboratory
Peer-Reviewed Publication

The first hours of a lithium-ion battery's life largely determine just how well it will perform. In those moments, a set of molecules self-assembles into a structure inside the battery that will affect the battery for years to come. Now scientists have witnessed the formation of the solid-electrolyte interphase at a molecular level.

Journal: Nature Nanotechnology
Funder: DOE's Office of Energy Efficiency and Renewable Energy's Vehicle Technologies Office, PNNL, the U.S.-Germany Cooperation on Energy Storage

Securing radiological sources on the go

DOE/Pacific Northwest National Laboratory
Business Announcement

Radioactive materials are a critical tool in a number of industrial applications, particularly oil and gas drilling and welding. But, if they are lost or stolen, the materials could be used by terrorists to make dirty bombs.

Funder: National Nuclear Security Administration

An out-of-the-box attack on diabetes

DOE/Pacific Northwest National Laboratory
Peer-Reviewed Publication

A protein newly identified as important in type 1 diabetes can delay onset of the disease in diabetic mice, providing a new target for prevention and treatment in people, according to research led by scientists at the US Department of Energy's Pacific Northwest National Laboratory and Indiana University School of Medicine.

Journal: Cell Metabolism
Funder: Fonds national suisse de la recherche scientifique, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Veterans Affairs Merit Review Award, and others

Predicting How Microbial Neighbors Influence Each Other

DOE/Pacific Northwest National Laboratory

Researchers developed a new theoretical framework called minimal interspecies interaction adjustment (MIIA). It predicts how surrounding organisms and other factors drive changes in interactions in microbial communities.

Simplifying microbial consortia opens a path to understanding soil community ecology

DOE/Pacific Northwest National Laboratory

New research demonstrates that microbial communities that are simplified but still representative may offer a way to explore more complex ones. In particular, they can help scientists uncover the mechanisms that drive the ecology of groups of soil microbes.

Droughts spell changes for soil microbes

DOE/Pacific Northwest National Laboratory

Scientists predict a warming Earth will cause more droughts that are more severe in the grasslands of the central United States. This research found that soil drying affects the microbial community in several ways.

When ions and molecules cluster

DOE/Pacific Northwest National Laboratory

How an ion behaves when isolated within an analytical instrument can differ from how it behaves in the environment. Now, Xue-Bin Wang at Pacific Northwest National Laboratory devised a way to bring ions and molecules together in clusters to better discover their properties and predict their behavior.

Scientists pinpoint cause of harmful dendrites and whiskers in lithium batteries

DOE/Pacific Northwest National Laboratory
Peer-Reviewed Publication

Scientists have uncovered a root cause of the growth of needle-like structures -- known as dendrites and whiskers -- that plague lithium batteries, sometimes causing a short circuit, failure, or even a fire. Such defects are a major factor holding back the batteries from even more widespread use and further improvement.

Journal: Nature Nanotechnology
Funder: US Department of Energy EERE Vehicle Technologies Office

Wei-Jun Qian

DOE/Pacific Northwest National Laboratory

Wei-Jun Qian is a staff scientist and team lead in the Integrative Omics group in the Biological Sciences Division of the Department of Energy's Pacific Northwest National Laboratory.

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