28-Jun-2006
A probable cause for Parkinson's?
DOE/Pacific Northwest National LaboratoryPeer-Reviewed Publication
A study by Pacific Northwest National Laboratory and UCLA's David Geffen School of Medicine reveals that damage in Parkinson's, Alzheimer's and other brain diseases is linked to a natural byproduct of metabolism and oxidative stress called nitration. Researchers surveyed nearly 8,000 proteins in a healthy mouse brain and found nitration on 31 sites along 29 different proteins, half of which had been previously implicated in several of the neurodegenerative diseases.
- Journal
- Biochemistry
- Funder
- DOE/US Department of Energy, National Institutes of Health