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29-Sep-2004
Pacific Northwest team unveils largest virus proteome to date
DOE/Pacific Northwest National LaboratoryPeer-Reviewed Publication
Scientists have discovered a record number of proteins for one of the largest and most complex viruses, the highly infectious and stealthy human cytomegalovirus, a team from Pacific Northwest National Laboratory and Oregon Health & Science University reported today in the October Journal of Virology.
- Journal
- Journal of Virology
- Funder
- DOE/US Department of Energy, National Institutes of Health
24-Sep-2004
Spun from bone
DOE/Pacific Northwest National LaboratoryPeer-Reviewed Publication
Bone and enamel start with the same calcium-phosphate crystal building material but end up quite different in structure and physical properties.
But how that protein achieves this feat of crystal-strand shape-shifting has remained elusive. Today, a Pacific Northwest National Laboratory-led team of scientists reports the first direct observation of how this protein, amelogenin, interacts with crystals like those in bone to form the hard, protective enamel of teeth.
- Journal
- Journal of Biological Chemistry
- Funder
- DOE/US Department of Energy, National Institutes of Health
14-Sep-2004
Peering inside the body, with a new spin—literally
DOE/Pacific Northwest National LaboratoryPeer-Reviewed Publication
A new NMR technique developed at the Pacific Northwest National Laboratory called slow-magic-angle spinning magnetic resonance spectroscopy, or "slow MAS" for short, has provided researchers a new glimpse inside living tissue and cells that other biomedical imaging methods cannot render.
- Funder
- DOE/US Department of Energy, National Institutes of Health
10-Sep-2004
PNNL lands $10.3 million NIH biodefense contract to unlock proteomes of salmonella and pox
DOE/Pacific Northwest National LaboratoryGrant and Award Announcement
Pacific Northwest National Laboratory begins a five-year, $10.3 million NIH project to identify the proteins that regulate the bacteria that cause salmonella poisoning, typhoid fever, and the monkey pox virus. The award is the Department of Energy lab's third $10 million NIH grant or contract in the past year.
- Funder
- National Institutes of Health
30-Aug-2004
Pacific Northwest National Laboratory gets $10 million from NIH to build virtual lung
DOE/Pacific Northwest National LaboratoryGrant and Award Announcement
Pacific Northwest National Laboratory will lead a $10 million, five-year multi-institutional National Institutes of Health study to devise 3-D imaging and computational models of unsurpassed detail of respiratory systems in humans and other mammals. The research will culminate in a "pulmonary physiome," a web-based model for researchers and clinicians.
- Funder
- National Institutes of Health
26-Aug-2004
Protein fishing in America: The movie
DOE/Pacific Northwest National LaboratoryPeer-Reviewed Publication
Proteins pass messages to other proteins much like fly-fishermen flicker their lines against water, or so a current leading theory holds. This vital exchange between single molecules has defied direct observation because that line-flicking and message-passing happen randomly at such a small scale. An instrument at the Pacific Northwest National Laboratory can reveal real-time interactions of single proteins, and its new results support the fly-fishing theory of protein communication.
- Funder
- DOE/US Department of Energy
- Meeting
- American Chemical Society 228th National Meeting
24-Aug-2004
Supercritical fluids—making nanoparticles easy
DOE/Pacific Northwest National Laboratory
It's not a liquid. It's not a gas. It's a supercritical fluid. Although it looks like a liquid, it has unique properties that allow scientists to work with it in ways they can't with liquids. Researchers at Pacific Northwest National Laboratory are using supercritical fluids as solvents in a process that creates nanoparticles.
24-Aug-2004
Thin films enable next-generation displays
DOE/Pacific Northwest National Laboratory
You've finished working on your computer and you're ready to call it a day. Instead of logging off and folding the screen down over a laptop keyboard, imagine rolling up the computer screen and stashing it in your bag. Roll-up computer screens and other flexible light-emitting displays that conform to almost any shape or surface may one day be realities thanks to a team of scientists at Pacific Northwest National Laboratory.
24-Aug-2004
Safe harbors in stormy waters
DOE/Pacific Northwest National Laboratory
Pacific Northwest National Laboratory's expertise in border control training is being tapped to support the Megaports Initiative, a government program aimed at preventing terrorism.