Rats may seek cannabis to cope with stress
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Updates every hour. Last Updated: 14-Dec-2025 23:11 ET (15-Dec-2025 04:11 GMT/UTC)
A fundamental discovery about phosphorylation, a key mechanism that enables nervous system connections to strengthen, may alter the textbook-level understanding of how synapses work. Phosphorylation is a biochemical process considered fundamental for functions within cells, such as metabolism, structural processes and subcellular signaling. It also occurs outside of cells, and scientist found in this study that kinases within the synaptic cleft play an important role in synaptic plasticity. The findings, published Nov. 20 in the journal Science, have direct implications for better understanding the underlying biochemical mechanisms involved in learning, memory and pain, creating broad implications for neuroscience.
Parents may have more influence than they realize when it comes to shaping their children’s behavior, especially for those at higher genetic risk for conduct problems, according to Rutgers Health-led research.
The study, published in Frontiers in Child and Adolescent Psychiatry, found that consistent parental monitoring – meaning knowing where children are, who they’re with, and what they’re doing – can help offset genetic risk for developing behavior problems during adolescence.
Cognition and neuroscience doctoral student Hailey Welch is the lead author of a study appearing online Nov. 5 in Cell Reports that examined the role of the vagus nerve’s branches in digestive signaling. She also has received a Ruth L. Kirschstein Fellowship from the National Institutes of Health to support her progress toward her doctorate at The University of Texas at Dallas. Her research charts the molecular and functional profiles of sensory neurons in the vagus nerve of rodents using genetic sequencing, imaging and functional assays, providing a potential explanation for why right-sided vagus nerve signaling activates the release in the brain of dopamine.
Young sexual minority men – a term used to describe gay, bisexual, and other men who have sex with men – with attention-deficit/hyperactivity disorder (ADHD) symptoms are more likely to begin using substances such as cigarettes, alcohol, cannabis, stimulants and illicit drugs at an earlier age, according to Rutgers Health researchers.
Researchers at Wayne State University will work with Michigan agencies and education partners to improve access to school-based substance use prevention and treatment programs for adolescents who are at risk of substance misuse and substance use disorders (SUDs) with the help of a NIH R61 grant.
Since 2019, overall rates of nicotine vaping have declined among U.S. youth, but those who continue to vape are showing signs of worsening addiction, according to new USC research. Between 2020 and 2024, the share of current users who vaped every day increased from 15.4% to 28.8%. Over the same period, the share of daily users who tried to quit but were unable to rose from 28.2% to 53%. The researchers analyzed the past five years of data from Monitoring the Future, an annual in-school survey that asks 8th, 10th and 12th graders across the country about their substance use. Over the study period, the demographics of youth vapers also changed. By 2024, more vapers were female, non-Hispanic Black or from a rural area. More youth vapers also reported using other substances, including alcohol and cannabis. Among youth in rural communities, daily vaping jumped dramatically—from 16.4% in 2020 to 41.8% in 2024, a spike that has prompted the study team to examine further. Masonbrink is now planning a follow-up study with youth in urban, suburban and rural areas to explore their experiences with nicotine product marketing and product access, as well as prevention and public health messaging.