Verification of signature gene expression revealed by scRNA-seq. (IMAGE)
Caption
(A) Key signature genes of KC and macrophage clusters from scRNA-seq analysis (B) Immunohistochemical staining of key signature genes on liver sections from healthy mice or mice treated with ConA for 72 hours. (C) Summary figure for the distribution of different populations of liver macrophages around the necrotic lesions of injured liver. ConA, concanavalin A; KCs, Kupffer cells; MoMFs, monocyte-derived macrophages; scRNA-seq, single-cell RNA sequencing.
Credit
By Dechun Feng, Yukun Guan, Yang Wang, Luca Maccioni, Bryan Mackowiak, Bin Gao.
Usage Restrictions
Credit must be given to the creator. Only noncommercial uses of the work are permitted.
License
CC BY-NC