Figure 2: CDCA completely suppressed conjunctivitis in SJS/TEN model mice (IMAGE)
Caption
To confirm the in vivo effectiveness of CDCA, the compound was administered to SJS/TEN mouse model that closely mimics the pathological features observed in human patients. Mice in the positive control group exhibited marked eyelid conjunctivitis (n = 7), whereas the CDCA-treated group showed no signs of conjunctivitis (n = 7).
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Modified from Kimura H et al., Nat Commun. 2025.
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