Figure 1: Validation of FPR1 inhibitor candidates using SJS/TEN model cell (IMAGE)

Niigata University

Figure 1: Validation of FPR1 inhibitor candidates using SJS/TEN model cell

Caption

The FPR1-inhibitory activity of the candidate compounds was evaluated using an in vitro SJS/TEN assay. Cell death inhibition was assessed by live/dead staining following treatment with various concentrations of each compound. Among the seven candidates, CDCA exhibited a specific and potent inhibitory effect on cell death, even at low concentrations.

Credit

Modified from Kimura H et al., Nat Commun. 2025.

Usage Restrictions

The image may only be used with appropriate caption or credit.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.