In vitro experiment of AMPs. (IMAGE)

First Hospital of Jilin University

In vitro experiment of AMPs.

Caption

(A) Bactericidal effect of five AMPs on two kinds of bacteria. (B) Cytotoxicity of five AMPs including LR, KC, KI, KP and WR to macrophages. (C) The bactericidal effect of LR against S. aureus, AB-29 and E. coli. (D) The bactericidal effect of KC against S. aureus, AB-29 and E. coli. (E) Cytotoxicity of LR and KC to macrophages and colon cancer cells. (F) The haemolytic activity of LR and KC. Data are presented as mean±SD (n=3). A. baumannii, Acinetobacter baumannii; AMPs, antimicrobial peptides; E. coli, Escherichia coli; LR, KC, KI, KP and WR, algorithm-generated AMPs; PBS, phosphate buffered saline; PI, propidium iodide; S. aureus, Staphylococcus aureus.

Credit

By Hui Miao, Ziwei Wang, Pengfei Cui, et al.

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted.

License

CC BY-NC

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.