Functional enrichment and gene expression analysis in TAC cells from AK versus WT corneas. (IMAGE)

Eye Discovery

Functional enrichment and gene expression analysis in TAC cells from AK versus WT corneas.

Caption

(A) Bar plot showing the top 30 GO terms enriched for upregulated genes in TAC cells from AK versus WT corneas.
(B) GSEA of the apoptosis pathway.
(C) Violin plots showing increased expression of selected genes in AK corneas compared with WT corneas.
(D) GSEA of the angiogenesis pathway showing enrichment of angiogenesis-related genes in AK corneas.
(E) Violin plots showing increased expression of Vegfa, Vegfd, Pgf, Hif1a, Flt1, and Adam8 in TAC cells from AK compared with WT corneas.
(F) Scatter plot of KEGG pathway enrichment and chord diagram of Reactome pathway enrichment for upregulated genes in TAC cells from AK versus WT corneas.

Credit

Lingling Yang

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License

CC BY-NC

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