Functional and pathway alterations in immune cells from AK versus WT corneas. (IMAGE)

Eye Discovery

Functional and pathway alterations in immune cells from AK versus WT corneas.

Caption

(A) Bar plot showing the top 10 GO biological process terms enriched for upregulated genes in monocyte–macrophage (Mono-Mac) cells from AK versus WT corneas.
(B) Dot plot of KEGG pathway enrichment for upregulated genes in Mono-Mac cells from AK versus WT corneas.
(C) Violin plots showing expression of selected genes (Hif1a, Eno1, Hmox1, Camk2d, Vegfa, and Pfkp) in Mono-Mac cells from AK and WT corneas.
(D) Bar plot showing the top 10 GO biological process terms enriched for upregulated genes in neutrophils from AK versus WT corneas.
(E) Dot plot of KEGG pathway enrichment for upregulated genes in neutrophils from AK versus WT corneas, indicating pathway dysregulation.
(F) Violin plots showing expression of selected genes (Nfkbia, Cxcl2, Tnf, Ccl4, Tnfrsf1a, and Il1b) in neutrophils from AK and WT corneas.

Credit

Lingling Yang

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License

CC BY-NC

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