The single-cell RNA sequencing analysis reveals diverse cell types and the distribution of PLXNC1 in the four CMS subtypes (IMAGE)

Compuscript Ltd

The single-cell RNA sequencing analysis reveals diverse cell types and the distribution of PLXNC1 in the four CMS subtypes

Caption

(A) tSNE visualization of 47285 cells from 23 tumor samples (GSE132465). (B) Violin plots showing specific gene markers in each cell type. (C) The compositions of the major cell components in different CMS subtypes. (D) Possible interaction strengths between the seven major cell types in CMS1–3 and CMS4 samples. (E) Heatmap of the difference in the communicational probability among cells. Red (positive values) and blue (negative values) indicate higher numbers of predicted interactions in CMS4 and CMS1–3, respectively. (F) tSNE visualization of the distribution of PLXNC1 in all samples. (G) tSNE visualization of the distribution of PLXNC1 in the four CMS subtypes.

Credit

Weiqi Wang, Mingxuan Zhou, Tiegang Li, Wenqiang Gan, Silin Lv, Zheng Yan, Yufang Hou, Zifan Zeng, Liu Yang, Fang Zhang, Wenyi Zhao, Min Yang

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted.

License

CC BY-NC-ND

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.