Expression of ATOX1 in Alzheimer's disease. (IMAGE)
Caption
(A) Western blot analysis of ATOX1 protein levels in the cortical and hippocampal samples from 5-month-old C57BJ/L mice. (B) Western blot analysis of ATOX1 protein levels in the hippocampal samples from 5-month-old wild-type and 5 × FAD mice. (C) Quantifications of ATOX1 protein levels. (D) The mRNA levels of ATOX1 in wild-type and 5 × FAD mice were detected by real-time PCR. ∗∗p < 0.01; t-test and Tukey's post hoc analysis. (E) Quantifications of ATOX1 mRNA levels in neurons, astrocytes, and microglia. (F) The ATOX1 protein levels in neurons, astrocytes, and microglia were detected by Western blot analysis. (G) Quantifications of ATOX1 protein levels. ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001; data were reported as mean ± standard error of the mean; one-way ANOVA with Tukey's post hoc analysis.
Credit
Fuxin Zhong, Jiani Wu, Zhangjing Deng, Wuhan Yu, Jiaqi Song, Yingxi Chen, Weihua Yu, Yang Lü
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