Fig. 5. (IMAGE)
Caption
Fig. 5. Nrf2 pathway responsive gene expression in zebrafish after treatment with the crude extract. Relative mRNA levels (fold change vs. negative control) of gstp1 and prdx1 (peroxiredoxin 1), two downstream target genes of the Nrf2 antioxidant-response pathway, were quantified by RT–qPCR in AB-strain zebrafish following exposure to 40 µM sulforaphane AB.SF (+) (positive control for Nrf2 activation) and crude extract (50 μg/mL) AB.Crude. Asterisks indicate statistical significance for the indicated comparisons: p < 0.01 (**), p < 0.001 (***), and p < 0.0001 (****); ns, not significant.
Credit
Minh Hien Nguyen, Minh-Tri Le, Khac-Minh Thai, Soo-Yeon Lee, Jin-Han Park
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