Like Google Maps in 3D for the Mouse Brain (VIDEO)

Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Caption

With the "BigStitcher" software you can reconstruct a sample and then rotate and turn it virtually, get an overview of the big picture or zoom into individual structures. This works both as a user, as illustrated here, and as an algorithm that analyzes the data and cannot load the entire image into RAM. Neurons expressing a specific gene are marked in green. Such data now make it possible for the first time to systematically characterize differences at the single-cell level between normal and genetically modified mice and to draw conclusions about potential behavioral changes that may result.

Credit

Preibisch Lab / Treier Lab, MDC

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