Pancreatic Ducts Harbor Progenitor-Like Cells (IMAGE)

Diabetes Research Institute Foundation

Pancreatic Ducts Harbor Progenitor-Like Cells

Caption

Human pancreatic section showing the epithelium of a large pancreatic duct harboring progenitor-like cells. These cells are characterized by expression of PDX1 (blue) and the BMP-7 receptor ALK3 (red), but not the ductal marker carbonic anhydrase II (CAII, green). When sorted and cultured in defined conditions, these cells are BMP-7 expandable and exhibit multipotent differentiation potential.

Credit

Diabetes Research Institute/University of Miami Miller School of Medicine

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