The Concept of Natural Reduction Expands the Traditional Four-Stage Classification of Fracture Healing (IMAGE)

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The Concept of Natural Reduction Expands the Traditional Four-Stage Classification of Fracture Healing

Caption

(A) Healing begins with hematoma and inflammation at the fracture site. (B) Soft callus (purple) is formed, which we show to organize as a bidirectional growth plate at the concave side of the fracture site. (C) The two growth plates drive growth in opposite directions. The result is a jack-like mechanical effect that moves the fragments toward straightening (red arrows). (D) Ossification produces hard callus (orange). (E) The shape of the bone is fine-tuned by remodeling.

Credit

<i>Developmental Cell</i>, Rot <i>et al.</i>

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