MES+HS ameliorates abnormalities in urinary and blood renal function parameters in ADR-induced NS (IMAGE)

Kumamoto University

MES+HS ameliorates abnormalities in urinary and blood renal function parameters in ADR-induced NS

Caption

(Left) Albumin leaking into the urine of pathological model mice increased after disease induction on day 7 and peaked on day 10. In the MES+HS-treated group, urinary albumin levels decreased by 50% on day 7 and by 75% on day 10 compared to the untreated group. MES+HS also had an inhibitory effect on proteinuria scores over time.

(Right) MES+HS treatment reduced pathogenesis-induced increases in serum creatinine levels by 36% and blood urea nitrogen (BUN) levels by 24%.

MES conditions: 0.1 millisecond pulse width, 55 pulses per second, 12 V; HS conditions: 42 degrees °C

Credit

Professor Hirofumi Kai

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<p>Adapted from Fig. 1 of <a href="https://www.nature.com/articles/s41598-020-75761-8">Teramoto, K. et.al., Scientific Reports, 2020</a>. It has been modified in part from the original. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p>

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