<i>CONNEXIN 30</i> Knockout Mouse and Cochlea after Cell Transplantation (IMAGE)
Caption
Gene knockout mice lacking the CONNEXIN 30 protein experience hearing loss due to sensory cells dysfunction as the ion potential of the sensory cells inside the inner ear decreases after birth. In this study, human iPS cells-derived cells were transplanted into Connexin 30 knockout mice during the embryonic stage. The transplanted cells were engrafted in the treated inner ear and some cells began expressing CONNEXIN 30 after seven days had passed.
Credit
Dr. Hiroki Takeda
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