Figure 3 (IMAGE) Institute for Basic Science Caption (a) Assembly of artificial organelles for energy generation. ATP synthase was reconstituted into CEx-GOx and bo3 oxidase was reconstituted into CEx-HRP. The two CEx were fused and were able to penetrate deep into spheroids. (b) Decrease in pH (-ΔpH) vs. glucose concentrations for different exosomes. Fused exosomes show a greater degree of pH decrease. (c) Changes in ATP production after FEx-1 uptake under different conditions. (d) Artificial organelles were able to penetrate deep into the spheroid. The top row shows FEx-1 (labeled red with rhodamine B), while the bottom row shows free HRP enzyme inside spheroids. (e) Overall ROS levels decreased on subjecting FEx-1 under glucose and DTT. Credit Institute for Basic Science Usage Restrictions Attribution Required License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.