Macrophages in the Lungs (Mouse Tissues) after Influenza Infection (IMAGE)
Caption
Influenza infections are characterized by massive influx of monocytes/macrophages in the lungs.
Although it is required to eliminate the virus, excessive inflammation contributes to the severity of the disease.
In this picture, researchers analyzed the presence of inflammatory monocytes/macrophages (in red) in the lungs after influenza infection using immunofluorescence on frozen lung sections. They observed that in absence of LTB4 signalling, there was an increased accumulation of inflammatory monocytes/macrophages that led to increased immunopathology and morbidity.
Credit
Erwan Pernet, Research Institute of the McGill University Health Centre
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