Antibodies Recognize (IMAGE)

The University of Osaka

Antibodies Recognize

Caption

Upper: Antibodies recognize and bind to their specific target on the surface of cells. In complement-dependent cytotoxicity (CDC), complement binds to antibodies and forms a membrane attack complex (MAC). The MAC disrupts the cell membrane and induces cell death. Lower: Induction of Th1 or Th2 response with adjuvants. Nucleic acid adjuvants induce Th1 cell-mediated immune response (cytotoxicity) and stimulate the production of mouse IgG2. Aluminum adjuvants induce Th2 humoral immune response (neutralization) and stimulate the production of mouse IgG1.

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Osaka University

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