Visualizing an Immune Response Derived from a Single T Cell (IMAGE)

Technical University of Munich (TUM)

Visualizing an Immune Response Derived from a Single T Cell

Caption

An immune response derived from a single T cell can be visualized directly ex vivo: Progeny of a specific single CD8 T cell is characterized by simultaneous expression of CD8 (x axis) and a defined heritable marker (y axis) setting it apart from all endogenous cells. Here every pixel stands for a cell. A color-coded heatmap indicates high (blue) and low cell density (red). The picture displays more than 20,000,000 cells, only a tiny fraction of which (within the black box) are derived from single transferred T cells.

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Photo by Uli Benz, copyright TU Muenchen.

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