image: Fluorescence staining for NRF2 (magenta), p53 (green), and nuclei (blue) in normal breast ducts (encircled by extracellular matrix in white) and invading triple-negative breast cancer cells surrounding the ducts. This material relates to a paper that appeared in the Apr. 14, 2019, issue of Science Signaling, published by AAAS. The paper, by E.J. Pereira at University of Virginia in Charlottesville, VA; and colleagues was titled, "Sporadic activation of an oxidative stress-dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies." view more
Credit: [Credit: Samples stained by E.J. Pereira and imaged by K.A. Janes]