Deep generative model of macrophage immune response for hepato-intestinal tumor therapy optimization
Peer-Reviewed Publication
Updates every hour. Last Updated: 30-Oct-2026 18:17 ET (30-Oct-2026 22:17 GMT/UTC)
A research paper by scientists at Central South University developed a bioinspired digital twin platform integrating variational representation learning with causal sequence modeling.
The research paper, published on Jun 16, 2026 in the journal Cyborg and Bionic Systems.
This study revealed the complete molecular mechanism by which P.g induced microglial ferroptosis through the NOX4/PPAR-α/PGC-1α pathway, thereby driving neuroinflammation and cognitive impairment, providing a molecular target and theoretical basis for drug repurposing targeting NOX4 to intervene in periodontitis-associated Alzheimer's disease.
To address this limitation, research teams led by Prof. Kai Zhang (University of Göttingen) and Prof. Rongxin Su (Tianjin University) have developed an integrated salt-assisted assembly (iSAA) that couples ion crosslinking with organic–inorganic co-assembly to construct nanofibril–crystal (NF-C) composite films exhibiting vivid, tunable interference colors. The work has been recently published in Research.