Engineers take a closer look at how a plant virus primes the immune system to fight cancer
Peer-Reviewed Publication
Updates every hour. Last Updated: 29-Dec-2025 00:11 ET (29-Dec-2025 05:11 GMT/UTC)
A virus that typically infects black-eyed peas is showing great promise as a low-cost, potent cancer immunotherapy—and researchers are uncovering why.
A new paper provides evidence of how PFAS, often called “forever chemicals,” correspond to epigenetic changes that can lead to cancers, neurological disorders and autoimmune conditions.
A new class of PRMT5 inhibitors, designed to exploit a genetic vulnerability in aggressive tumors, works even better when paired with MAPK pathway drugs—wiping out hard-to-treat lung, brain, and pancreatic cancers in preclinical models, according to Virginia Tech scientists.
A new study led by Stephen D. Nimer, M.D.,director of Sylvester Comprehensive Cancer Center, shows how a key molecule regulates the generation of new blood cells, a process called hematopoiesis that goes awry in cancer. The findings have the potential to lead to new therapeutic strategies targeting the molecule, a regulator of gene activity called TAF1.
Preoperative delay when treating breast cancer confers poorer outcomes, but growth rates and the upstaging likelihoods per delay interval remain unknown. This study evaluated upstaging risk, nodal spread, and tumor growth rates in vivo while awaiting treatment.
A new article appearing in the current issue of the peer-reviewed Journal of Agriculture and Food Chemistry explores the concept of “superfoods” and makes a case that fresh grapes have earned what should be a prominent position in the superfood family.[1] The author, leading resveratrol and cancer researcher John M. Pezzuto, Ph.D., D.Sc., Dean of the College of Pharmacy and Health Sciences at Western New England University, brings forth an array of evidence to support his perspective on this issue.
[1] Pezzuto, John M. (2025). Perspective: Are Grapes Worthy of the Moniker Superfood? J. Agric. Food Chem. Doi: 10.1021/acs.jafc.5c05738
The diagnosis of a suspected lung, head, and neck cancer called NUT carcinoma should include additional testing capable of detecting gene fusions that are definitive markers of the disease, according to a study by Dana-Farber Cancer Instituteinvestigators. The study showed that more than 75 percent of patients with NUT carcinoma may not be immediately diagnosed because standard-of-care DNA testing does not detect NUT carcinoma fusion genes.