Enhanced CAR T cell therapy offers new strategy for lymphoma
Peer-Reviewed Publication
Updates every hour. Last Updated: 5-Nov-2025 21:11 ET (6-Nov-2025 02:11 GMT/UTC)
WEHI scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines for viruses and enhanced cancer therapies.
The WEHI-led study used a novel approach combined with cutting-edge mRNA vaccine technology to increase the formation of a type of T cell which has remarkable self-renewing capacity and can remember threats for years and even decades.
Scientists have discoverd that nucleosomes have their own biophysical properties that influence gene expression and 3D genome architecture.
A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed by scientists at Institut Curie, the CNRS, and Inserm. This crucial advance in the fight against metastatic cancer is based on identifying the cellular site for ferroptosis initiation, a natural process, catalysed by iron, that sparks the oxidative degradation of cell membranes. These promising preclinical results will be published in the journal Nature on 7 May 2025.
Presented at ESTRO 2025, which gathered a record attendance of 7,908 participants this week in Vienna, Austria, a 10-year study, involving over 4,000 UK patients, confirms that a one-week course of post-surgery radiotherapy is just as safe and effective as the traditional three-week regimen for early-stage breast cancer patients. These long-term results from the FAST-Forward trial, could further reduce the burden on breast cancer patients worldwide, and expand access to life-saving radiotherapy.